A Path With Paws

Si Miao San or Four Marvels Powder is truly one of the workhorses of Chinese medicine. It is probably the most common formula I use. You see, Si Miao San is very good at treating inflammation and our animal companions have a lot of inflammatory disorders. This is my top formula for inflammatory bowel disease, allergic dermatitis, Cushings disease, and diabetes.

Please follow this link to buy Si Miao San from my etsy store Kingdom of Basil Si Miao San powder.

For more information on Cushings disease see my article Managing Cushings Disease in Dogs Holistically.

In Chinese medicine it treats damp heat and is a simple yet powerful little formula of four ingredients.

• Huang Bai (phellodendron bark)
• Yi Yi Ren (coix seed)
• Cang Zhu (atractylodes rhizome)
• Huai Niu Xi (achyranthes root)

These ingredients are highly anti-inflammatory and often this formula can take the place of prednisone for inflammatory disorders but without the side effects.

So how does this formula work for cancer?

It’s two main ingredients, Huang Bai and Yi Yi Ren, both have anticancer actions. Huang Bai contains berberine, which has been shown in a number of studies to slow down tumor growth and induce apoptosis or cell death. If you search pub med you will find a large list of studies on berberine and its anti-cancer activities.
Here is a good one – Apoptosis of human leukemia cells and murine leukemia cells induced by berberine through activation of caspase

Coix seed also inhibits growth of cancer cells and can induce apoptosis. Here is a great article on coix seed and its cancer actions –
Healthy Doses Job’s tears

This formula can enhance the action of chemotherapy drugs and anti-microbials in a good way. So it can safely be used with chemotherapy. However often times I focus more on the herbals that have strong immune stimulant effects for animals who are receiving chemo.

The main cancer I use Si Miao San for is lymphoma and some of the leukemias. I also often use this formula if animals can not handle Hoxsey-like formula. Animals needing this formula will run hot and often times have a history of past inflammatory diseases.

The Cang Zhu in this formula helps to support good digestion, which can often be a large issue in animals with cancer. While most of this formula is very cold in nature, the atractylodes is warm and makes sure this formula is well tolerated by most animals. It also does not cool them down too much.

For the animals I treat I make my own Si Miao San from whole dried herbs and dose at 1/8 twice a day for cats and small dogs, ¼ teaspoon twice a day for dogs 15-25 lbs, ½ twice a day for dogs 25-50 lbs, 1 teaspoon twice a day for dogs 50-90lb and 1 ½ teaspoons twice a day for dogs greater than 90lbs.

With tinctures I use .2 ml per 5 lbs of animal twice a day. For tea pills and granules, use the human dose for dogs greater than 50lbs and dose down by weight for smaller animals.

If you are working with a holistic vet or Chinese herbalist, get this formula from them. I am now selling powdered Si Miao San out of my herbal shop Kingdom of Basil on etsy. Amazon does sell the Kan Herbs – Four Marvels pills

As with all supplements and herbals, please check with your animal’s regular vet before using this herbal.

Return to Integrative and Holistic Methods for Treating Cancer in Cats and Dogs

Lymphoma is one of the fastest moving cancers out there. Because it is so fast moving, it is also the most responsive cancer to chemotherapy.

The prognosis with this disease can be very bad, especially if no treatment is used.

However the good news is, with chemotherapy and holistic medicine we can often get 18-24 months and occasionally ongoing remission. Integrative medicine clearly is the best way to go with this disease.

With no treatment I have seen animals die within one week of diagnosis. The average is 4 weeks with no treatment. With using natural medicine, I have found usually I can move that out to 2-4 months. Chemotherapy alone pushes that even further with average survival at around a year.

When a dog or cat comes to me with lymphoma, I highly recommend they consult with an oncologist or a vet who does a lot of chemotherapy work. If you want remission with this cancer you need to do chemotherapy.

The most widely used chemotherapy protocol for this cancer consisted of a multiple drug approach and is given over approximately six months for dogs. In cats the protocol is shorter and the main vet I work with believes that one to three chemo treatments can significantly slow down this disease in felines.

Full chemotherapy for dogs can also be quite expensive, around $4000. Shorter durations can be given for this cancer as well if cost or tolerance of chemotherapy is a concern.

Because so many people choice to do chemotherapy for this cancer I divided this article into four sections.

• Treatments I recommend regardless of western treatment
• Treatments I use with chemo
• Treatments to give if no chemotherapy is used
• Cats

So first what do I recommend for all cats and dogs with lymphoma? (Follow the links for more information on the supplements and dosing information.)

1. Weekly or every other week acupuncture. I have seen this make a large difference in survival times and in keeping white blood cell levels within normal range during chemotherapy. Usually just with acupuncture alone I can double any prognosis. Please see Acupuncture for animals with cancer – stoking the healing power within
2. Artemisinin can reduce node size and make animals feel better.
3. A good cancer diet without grains. If you are using chemo do not feed raw food, make sure it is cooked. For more information on the diets I recommend seeDiets for cancer in cats and dogs.
4. Xiao Chai Hu Tang – Sometimes I add indigo and others herbs to this formula for dogs I see in person to customize it but the straight formula works well also. If you are working with a holistic vet ask them about additions.

In addition to this protocol if no chemo is used I often recommend –

1. Prednisone. Yes it is a western drug, but it will work as a chemotherapy drug and shrink the nodes. Every animal I have treated for lymphoma has been on prednisone and I highly recommend it. If you are considering chemo do not start the prednisone before consulting with an oncologist or vet who knows chemo. If given before chemo the prednisone can significantly reduce the outcome of the chemo.
2. SanSheDan ChuanBeiYe is great at slowing this cancer down and keeping it out of the lungs.



3. Hoxsey-like formula or Cancer Detox Support Hoxsey can make some dogs sick, I usually only recommend using it if you are working directly with a holistic vet who thinks it is appropriate. I also use a similar formula I call cancer detox which is less toxic but still has some great anti-cancer properties.
Si Miao San I use a lot less of this these days but still sometimes if the lymphoma is mostly in the nodes or gastrointestinal system.

If chemotherapy is given I add to my main protocol:

1. Mushrooms – I give a mushroom combo with shiitake, maitaki, reishi and cordyceps There are many of these products. Mushrooms not only have effects directly against cancer but stimulate the immune system and help keep white blood cell counts up.
2. Milk thistle – improves the outcome of chemotherapy and decreases side effects
3. Bu Zhong Yi Qi Tang – there is a great study out there at shows this herbal improves outcomes and reduces side effects during chemotherapy.

In cats

Cats have a hard time with multiple drugs and supplements. With cats I start them on my main protocol and then wait a week. If they are still eating well I will then add in one Chinese herbal formula in addition to my main protocol.

How do I decide which one?

The best I can tell you is usually this will either be Xiao Chai Hu Tang if this cancer is intestinal or centered in the spleen or liver, Hoxsey-like formula if the cancer is in the nodes, or Bu Zhong Yi Qi Tang if they are getting chemotherapy.

If at all possible find a good holistic practitioner to work with your cat. Cats generally do really well with acupuncture so if at all possible find someone who also does acupuncture.

Cats can get a disease called small cell lymphoma which is very slow moving. I treat this differently and will try to put up another article on it.

As with all advice offered on this website please check in with your animal’s primary veterinarian before using any of these herbals and supplements.

Return to Integrative and Holistic Methods for Treating Cancer in Cats and Dogs