Si Miao San – slowing down cancer and inflammation
Friday, June 17th, 2011Si Miao San or Four Marvels Powder is truly one of the workhorses of Chinese medicine. It is probably the most common formula I use. You see, Si Miao San is very good at treating inflammation and our animal companions have a lot of inflammatory disorders. This is my top formula for inflammatory bowel disease, allergic dermatitis, Cushings disease, and diabetes.
Please follow this link to buy Si Miao San from my etsy store Kingdom of Basil Si Miao San powder.
For more information on Cushings disease see my article Managing Cushings Disease in Dogs Holistically.
In Chinese medicine it treats damp heat and is a simple yet powerful little formula of four ingredients.
- Huang Bai (phellodendron bark)
- Yi Yi Ren (coix seed)
- Cang Zhu (atractylodes rhizome)
- Huai Niu Xi (achyranthes root)
These ingredients are highly anti-inflammatory and often this formula can take the place of prednisone for inflammatory disorders but without the side effects.
So how does this formula work for cancer?
It’s two main ingredients, Huang Bai and Yi Yi Ren, both have anticancer actions. Huang Bai contains berberine, which has been shown in a number of studies to slow down tumor growth and induce apoptosis or cell death. If you search pub med you will find a large list of studies on berberine and its anti-cancer activities.
Here is a good one – Apoptosis of human leukemia cells and murine leukemia cells induced by berberine through activation of caspase
Coix seed also inhibits growth of cancer cells and can induce apoptosis. Here is a great article on coix seed and its cancer actions –
Healthy Doses Job’s tears
This formula can enhance the action of chemotherapy drugs and anti-microbials in a good way. So it can safely be used with chemotherapy. However often times I focus more on the herbals that have strong immune stimulant effects for animals who are receiving chemo.
The main cancer I use Si Miao San for is lymphoma and some of the leukemias. I also often use this formula if animals can not handle Hoxsey-like formula. Animals needing this formula will run hot and often times have a history of past inflammatory diseases.
The Cang Zhu in this formula helps to support good digestion, which can often be a large issue in animals with cancer. While most of this formula is very cold in nature, the atractylodes is warm and makes sure this formula is well tolerated by most animals. It also does not cool them down too much.
For the animals I treat I make my own Si Miao San from whole dried herbs and dose at 1/8 twice a day for cats and small dogs, ¼ teaspoon twice a day for dogs 15-25 lbs, ½ twice a day for dogs 25-50 lbs, 1 teaspoon twice a day for dogs 50-90lb and 1 ½ teaspoons twice a day for dogs greater than 90lbs.
With tinctures I use .2 ml per 5 lbs of animal twice a day. For tea pills and granules, use the human dose for dogs greater than 50lbs and dose down by weight for smaller animals.
If you are working with a holistic vet or Chinese herbalist, get this formula from them. I am now selling powdered Si Miao San out of my herbal shop Kingdom of Basil on etsy. Amazon does sell the Kan Herbs – Four Marvels pills
As with all supplements and herbals, please check with your animal’s regular vet before using this herbal.
Return to Integrative and Holistic Methods for Treating Cancer in Cats and Dogs






















Just an interesting side note. The Chinese consider stroke to be a sudden rush of wind to the head which then has a hard time escaping the body and bounces around. One of the main herbs I use for stroke is an herb called Bai Ji Li or caltrop fruit. This herb helps to open up the body so the wind can escape and the body can heal. Check out the shape of the fruit. They are pointed to open up holes for the wind to escape through. I love when you can look at an herb and see it’s function!
On Mondays, I descend down into the basement to disappear into my world of herbs. Once there I spend a couple hours smelling, touching and tasting, to create formulas to help the animals I work with. As I work I can hear the ancient wisdom of the past herbal masters whispering to me and feel the vibrations of these plants, many which were on this planet before us. To me working with these herbs is like cooking, only I am making up a recipe for healing by harnessing the amazing powers of these living things.
One of my clients is a paralyzed dachshund. Making up a formula for him, I call upon four of my favorite herbs to form a blood tonic. The four are all roots – foxglove, peony, Chinese angelica, and lovage – and are earthy and strong. I love to tea these in the winter and sit on my window seat sipping the strong rich tea they make. I can feel how these herbs work to strengthen me from the inside so that I have the energy to heal. This is what I want for this little dog.
Most of these dachshunds have closed channels because of traumatic disc injury. I can tonify the blood all I want but it is like trying to send water down a plugged hose. I add a handful of earthworms into this formula, which the Chinese say get into the blood channels and wiggle them open like a roto rooter opening a clogged drain.


